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Updated: Apr 28, 2026

A Step Beyond BRET: Fluorescence by Unbound Excitation from Luminescence FUEL
Published on: May 23, 2014
Original Design of Fluorescent Ligands by Fusing BODIPY and Melatonin Neurohormone
Jérémy Thireau1, Justine Marteaux1, Philippe Delagrange2
1Université d'Orléans , CNRS, ICOA, UMR 7311, F-45067 Orleans, France.
Abstract:
An original design and synthesis of fluorescent ligands for melatonin receptor studies is presented and consists in the fusion of the endogenous ligand with the fluorescent BODIPY core. Probes I-IV show high affinities for MT1 and MT2 melatonin receptors and exhibit fluorescence properties compatible with cell observation.
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