Related Experiment Video
Updated: Apr 28, 2026

Author Spotlight: Enhancing Vascular Function and Physical Capacity in Cardiovascular Disease Through Novel Interventions and NIRS Technology
Published on: March 22, 2024
Blood flow restriction: effects of cuff type on fatigue and perceptual responses to resistance exercise
J P Loenneke1, R S Thiebaud2, C A Fahs2
1The University of Oklahoma Department of Health and Exercise Science, Neuromuscular Research Laboratory Norman OK USA 1401 Asp Avenue, Room 104 Norman OK 73019-0615 USA.
Abstract:
Blood flow restriction (BFR) combined with low load resistance training has been shown to result in muscle hypertrophy similar to that observed with higher loads. However, not all studies have found BFR efficacious, possibly due to methodological differences. It is presently unclear whether there are differences between cuffs of similar size (5 cm) but different material (nylon vs. elastic). The purpose was to determine if there are differences in repetitions to fatigue and perceptual ratings of exertion (RPE) and discomfort between narrow elastic and narrow nylon cuffs. Sixteen males and females completed three sets of BFR knee extension exercise in a randomized cross-over design using either elastic or nylon restrictive cuffs applied at the proximal thigh. There were no differences in repetitions to fatigue (marker of blood flow) or perceptual ratings between narrow elastic and narrow nylon cuffs. This data suggests that either elastic or nylon cuffs of the same width should cause similar degrees of BFR at the same pressure during resistance exercise.
Related Concept Videos
Pre-Procedural Guidelines for Assessing Blood Pressure
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Sites for measuring blood pressure
The Brachial Artery: Primary Site for Blood Pressure Measurement

