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Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

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The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
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Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80%...
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The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
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Chronic Pancreatitis II: Pathophysiology01:21

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Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...
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Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

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Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
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Chronic Bowel Disorders: Introduction

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Articles linked to this work by shared authors, journal, and citation graph.

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[Erratum to: Diagnosis and treatment of interstitial cystitis (IC/PBS). S2k guideline of the German Society of Urology].

Der Urologe. Ausg. A·2019
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[Diagnosis and treatment of interstitial cystitis (IC/PBS) : S2k guideline of the German Society of Urology].

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[Acute inpatient multimodal pain therapy and rehabilitation: Framework conditions, tasks and differentiated patient allocation].

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[Chronic pelvic pain: alternative treatment methods].

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[Multimodal pain therapy for treatment of chronic pain syndrome. Consensus paper of the ad hoc commission on multimodal interdisciplinary pain management of the German Pain Society on treatment contents].

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[Capsaicin plasters for complex regional pain syndrome type II].

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Related Experiment Video

Updated: Apr 28, 2026

Author Spotlight: Enhancing Women's Chronic Pelvic Pain Management Through Acupoint Catgut Embedding
02:41

Author Spotlight: Enhancing Women's Chronic Pelvic Pain Management Through Acupoint Catgut Embedding

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[Chronic pelvic pain].

O Moormann1, I Gralow

  • 1Klinik für Urologie, St.-Josefs-Hospital, Wilhelm-Schmidt-Str.4, 44263, Dortmund, Deutschland, o.moormann@lukas-gesellschaft.de.

Schmerz (Berlin, Germany)
|June 7, 2014
PubMed
Summary
This summary is machine-generated.

Chronic pelvic pain (CPP) is complex with no standard treatments. Multimodal therapy, successful in other chronic pain conditions, is recommended for CPP when standard treatments fail.

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Area of Science:

  • Urology
  • Gynecology
  • Pain Medicine

Context:

  • Chronic pelvic pain (CPP) is a prevalent condition with unknown causes.
  • Current diagnostic and therapeutic approaches lack international standardization.

Purpose:

  • To review the prevalence and therapy of chronic pelvic pain syndrome.
  • To identify effective treatment strategies for chronic pelvic pain.

Summary:

  • A literature search identified systematic reviews and guidelines for CPP prevalence and therapy.
  • Multimodal therapy concepts are recommended when established treatments are ineffective.
  • Evidence-based, controlled studies for CPP are currently lacking.

Impact:

  • The success of multimodal approaches in other chronic pain conditions suggests potential for CPP.
  • This review highlights the need for developing and verifying multimodal therapies for chronic pelvic pain.