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Updated: Apr 28, 2026

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Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
Published on: January 21, 2020
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[Complex regional pain syndrome: A current review].
1Klinik für Neurologie, Klinikum Fürth, Jakob-Henle-Str. 1, 90766, Fürth, Deutschland, neurologie@klinikum-fuerth.de.
Summary
Complex regional pain syndrome (CRPS) can occur after injury and presents with autonomic, sensory, and motor issues. Treatment involves a multidisciplinary approach with physical therapy and symptom-based medications.
Area of Science:
- Neurology
- Pain Medicine
- Physical Rehabilitation
Context:
- Complex regional pain syndrome (CRPS) can arise after fractures, limb trauma, or nervous system lesions.
- It presents with a distinct triad of autonomic, sensory, and motor dysfunction.
- Diagnosis relies on clinical presentation adhering to the Budapest criteria.
Purpose:
- To outline the diagnostic criteria and therapeutic strategies for Complex regional pain syndrome (CRPS).
- To emphasize the individualized and multidisciplinary nature of CRPS management.
- To detail the pharmacological and physical therapy interventions for CRPS.
Summary:
- CRPS involves autonomic, sensory, and motor disturbances following trauma or nerve injury.
- Diagnosis is clinical, guided by the Budapest criteria.
- Treatment integrates physical therapy, pharmacotherapy (steroids, neuropathic pain agents, bone metabolism modulators), and potentially invasive methods.
Impact:
- Provides a concise overview of CRPS diagnosis and management.
- Highlights the importance of a multidisciplinary approach for effective patient care.
- Informs clinicians on current therapeutic options for CRPS patients.
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