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Updated: Apr 28, 2026

High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue
Published on: September 30, 2022
X-ray phase-contrast imaging at 100 keV on a conventional source
11] Paul Scherrer Institute, Villigen PSI, Switzerland [2] Institute for Biomedical Engineering, Swiss Federal Institute of Technology, Zurich, Switzerland.
Abstract:
X-ray grating interferometry is a promising imaging technique sensitive to attenuation, refraction and scattering of the radiation. Applications of this technique in the energy range between 80 and 150 keV pose severe technical challenges, and are still mostly unexplored. Phase-contrast X-ray imaging at such high energies is of relevant scientific and industrial interest, in particular for the investigation of strongly absorbing or thick materials as well as for medical imaging. Here we show the successful implementation of a Talbot-Lau interferometer operated at 100 keV using a conventional X-ray tube and a compact geometry, with a total length of 54 cm. We present the edge-on illumination of the gratings in order to overcome the current fabrication limits. Finally, the curved structures match the beam divergence and allow a large field of view on a short and efficient setup.
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