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Updated: Apr 28, 2026

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
Published on: April 11, 2018
Soft tissue sarcoma: an update on systemic treatment options for patients with advanced disease
Patrick Schöffski1, Jasmien Cornillie, Agnieszka Wozniak
1Department of General Medical Oncology and Laboratory of Experimental Oncology, Leuven Cancer Institute, KU Leuven, Belgium.
Abstract:
Sarcomas are a group of rare solid tumours arising from mesenchymal or connective tissue. This review focuses on soft tissue sarcoma and covers general topics such as the epidemiology, age distribution, site of disease, histogenesis, histological subtypes, prognosis and outcome of treatment. In more detail, the article reviews current systemic treatment standards and selected adverse events of agents such as doxorubicin, ifosfamide, trabectedin and pazopanib, and briefly highlights some drugs that are used off-label in specific subtypes of sarcoma.
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