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Extremely delayed brain metastasis from renal cell carcinoma
Won Ho Choi1, Young-Cho Koh1, Sang Woo Song1
1Department of Neurosurgery, Konkuk University Medical Center, Seoul, Korea.
Brain Tumor Research and Treatment
|June 7, 2014
Summary
Renal cell carcinoma (RCC) brain metastases can occur years after treatment. This case highlights extremely late brain metastases 18 years post-nephrectomy, suggesting a good prognosis for delayed occurrences.
Area of Science:
- Oncology
- Nephrology
- Neurology
Background:
- Brain metastasis is a known complication of renal cell carcinoma (RCC).
- The typical interval from nephrectomy to brain metastasis is 1-3 years.
- Delayed brain metastases (>10 years) from RCC are rare but associated with a better prognosis.
Purpose of the Study:
- To report an unusual case of extremely late brain metastasis from RCC.
- To emphasize the importance of considering delayed metastases in RCC survivors.
- To highlight the favorable prognosis associated with delayed central nervous system metastasis.
Main Methods:
- Case report of a 76-year-old female patient.
- Review of medical history including nephrectomy for RCC.
- Diagnostic confirmation of multiple brain metastases.
Main Results:
- The patient developed multiple brain metastases 18 years after nephrectomy for RCC.
- This represents an exceptionally long interval for CNS metastasis from RCC.
- The patient's presentation suggests a potentially good prognosis despite the late occurrence.
Conclusions:
- Extremely late brain metastases from RCC can occur, significantly beyond the typical timeframe.
- Histopathological confirmation and aggressive treatment are crucial for these delayed cases.
- Delayed brain metastases in RCC patients may indicate long survival and a good prognosis.
