Related Experiment Video
Updated: Apr 28, 2026

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data
Published on: June 26, 2013
Application of supernodal sparse factorization and inversion to the estimation of (co)variance components by residual
1Department of Life Science and Agriculture, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan.
Abstract:
We demonstrated that supernodal techniques were more efficient than traditional methods for factorization and inversion of a coefficient matrix of mixed model equations (MME), which are often required in residual maximum likelihood (REML). Supernodal left-looking and inverse multifrontal algorithms were employed for sparse factorization and inversion, respectively. The approximate minimum degree or multilevel nested dissection was used for ordering. A new computer package, Yet Another MME Solver (YAMS), was developed and compared with FSPAK with respect to computing time and size of temporary memory for 13 test matrices. The matrices were produced by fitting animal models to dairy data and by using simulations from sire, sire-maternal grand sire, maternal and dominance models for phenotypic data and animal model for genomic data. The order of matrices ranged from 32,840 to 1,048,872. The YAMS software factorized and inverted the matrices up to 13 and 10 times faster than FSPAK, respectively, when an appropriate ordering strategy was applied. The YAMS package required at most 282 MB and 512 MB of temporary memory for factorization and inversion, respectively. Processing time per iteration in average information REML was reduced, using YAMS. The YAMS package is freely available on request by contacting the corresponding author.
Related Concept Videos
Residuals and Least-Squares Property
If the observed data point lies above the line, the residual is positive, and the line underestimates the actual data value for y. If the observed data point lies below the line, the residual is negative, and the line overestimates the actual data value for y.
The process of fitting the best-fit...
Vector Algebra: Method of Components
In many applications, the magnitudes and directions of...
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation
On...
Extraction: Partition and Distribution Coefficients
For extracting a solute from an aqueous phase into an...
Application of Linearization and Approximation
Linear Approximation in Frequency Domain
In contrast, nonlinear systems do not inherently possess these properties. However, for small deviations around an operating point, a nonlinear system can often be approximated as linear....

