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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Related Experiment Video

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Iris Fixation via External Pentagram Suturing
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Iridocorneal endothelial syndrome.

Adnan Aslam Saleem1, Mahmood Ali1, Farah Akhtar1

  • 1Department of Ophthalmology, Al-Shifa Trust Eye Hospital, Rawalpindi.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|June 8, 2014
PubMed
Summary

This case report details a rare instance of iridocorneal endothelial syndrome in a teenage male, presenting with unilateral vision loss and glaucoma. Early diagnosis and management are crucial for this uncommon condition.

Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Corneal Diseases

Background:

  • Iridocorneal endothelial syndrome (ICES) is a spectrum of disorders characterized by abnormalities of the corneal endothelium, iris, and anterior chamber angle.
  • This condition can lead to secondary glaucoma and vision loss, necessitating prompt diagnosis and treatment.

Observation:

  • A 19-year-old male presented with a two-year history of reduced and fluctuating vision, pupillary shape changes, and iris color alteration in his left eye.
  • Ocular examination revealed unilateral stretch holes, iris atrophy, elevated intraocular pressure (36 mmHg) in the left eye, and peripheral anterior synechiae.
  • Specular microscopy demonstrated abnormal corneal endothelium with irregularly shaped cells.

Findings:

  • The patient exhibited signs consistent with iridocorneal endothelial syndrome, including unilateral corneal and iris abnormalities.

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  • Elevated intraocular pressure and optic disc cupping indicated secondary glaucoma.
  • This represents the second reported case of ICES in a male teenager.

    • Implications:

    • This case highlights the importance of considering ICES in young males presenting with unilateral glaucoma and iris abnormalities.
    • Further research into the etiology and long-term management of ICES in adolescents is warranted.
    • Increased awareness among ophthalmologists can facilitate earlier diagnosis and intervention, potentially preserving vision.