Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Predicting Low and Non-Responders and Outliers in Patients with Spinal Cord Injury.

Journal of clinical medicine·2026
Same author

Paravertebral intramuscular and rectal insufflation oxygen-ozone therapy for modic 1- related low back pain: a case report.

Journal of bodywork and movement therapies·2026
Same author

Motor and cognitive effects of video game training in people with multiple sclerosis: a randomized controlled trial.

European journal of physical and rehabilitation medicine·2026
Same author

Urinary Exosomal microRNAs as a Novel Approach to Study People with Multiple Sclerosis and Severe Gait Disability: A Preliminary Observation.

Non-coding RNA·2026
Same author

Exploring the Role of <i>Cissus quadrangularis</i> in Osteoporosis Management.

Orthopedic research and reviews·2026
Same author

The adoption of innovative technologies in Physical and Rehabilitation Medicine: state of the art and unmet needs.

European journal of physical and rehabilitation medicine·2026

Related Experiment Video

Updated: Apr 28, 2026

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis
08:48

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis

Published on: January 29, 2016

16.2K

A task-oriented circuit training in multiple sclerosis: a feasibility study.

Sofia Straudi1, Carlotta Martinuzzi, Claudia Pavarelli

  • 1Neuroscience and Rehabilitation Department, Ferrara University Hospital, Ferrara, Italy. s.straudi@ospfe.it.

BMC Neurology
|June 8, 2014
PubMed
Summary

High-intensity task-oriented circuit training (TOCT) improved walking ability and quality of life in multiple sclerosis (MS) patients. This safe and feasible program, followed by a home exercise plan, offers benefits for individuals with moderate mobility impairments.

More Related Videos

Author Spotlight: Enhancing Upper Limb Rehabilitation in Stroke Patients Through Advanced Robotic and Neuromodulation Technologies
05:28

Author Spotlight: Enhancing Upper Limb Rehabilitation in Stroke Patients Through Advanced Robotic and Neuromodulation Technologies

Published on: October 11, 2024

1.4K
Paradigms of Lower Extremity Electrical Stimulation Training After Spinal Cord Injury
08:07

Paradigms of Lower Extremity Electrical Stimulation Training After Spinal Cord Injury

Published on: February 1, 2018

12.4K

Related Experiment Videos

Last Updated: Apr 28, 2026

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis
08:48

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis

Published on: January 29, 2016

16.2K
Author Spotlight: Enhancing Upper Limb Rehabilitation in Stroke Patients Through Advanced Robotic and Neuromodulation Technologies
05:28

Author Spotlight: Enhancing Upper Limb Rehabilitation in Stroke Patients Through Advanced Robotic and Neuromodulation Technologies

Published on: October 11, 2024

1.4K
Paradigms of Lower Extremity Electrical Stimulation Training After Spinal Cord Injury
08:07

Paradigms of Lower Extremity Electrical Stimulation Training After Spinal Cord Injury

Published on: February 1, 2018

12.4K

Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Exercise Science

Background:

  • Multiple Sclerosis (MS) is a chronic neurological disease impacting mobility and quality of life.
  • Task-Oriented Circuit Training (TOCT) is a rehabilitative approach designed to improve functional abilities.
  • Evaluating novel training interventions is crucial for managing MS symptoms.

Purpose of the Study:

  • To assess the safety and feasibility of a high-intensity TOCT program in MS patients.
  • To investigate the preliminary effects of TOCT on walking competency, mobility, fatigue, and health-related quality of life (HRQoL).
  • To determine the long-term effects of a subsequent home exercise program.

Main Methods:

  • 24 MS subjects (EDSS 4.89 ± 0.54) were randomized into an experimental TOCT group or a control group.
  • The experimental group underwent 10 TOCT sessions over 2 weeks, followed by a 3-month home exercise program.
  • Functional outcomes included walking endurance, gait speed, mobility, balance, motor fatigue, walking ability, and HRQoL, assessed at baseline, post-intervention, and 3-month follow-up.

Main Results:

  • Subjects reported positive feedback on the TOCT intervention.
  • A 58.33% adherence rate was observed for the home-exercise program at 3 months.
  • Significant improvements in walking ability and HRQoL were noted post-TOCT (p < 0.05), with some retention at 3 months. The control group showed no significant changes.

Conclusions:

  • High-intensity TOCT followed by a home-based exercise program is feasible and safe for MS patients with moderate mobility impairments.
  • The intervention shows potential for improving walking abilities in this population.
  • Further research may explore optimizing TOCT protocols for sustained functional gains.