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Probiotics and prebiotics in dermatology
Katherine L Baquerizo Nole1, Elizabeth Yim1, Jonette E Keri2
1Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida.
Journal of the American Academy of Dermatology
|June 8, 2014
Summary
Probiotics and prebiotics show promise in preventing infant atopic dermatitis, but their effectiveness in treatment remains debated. Further research is needed for applications in acne, wound healing, and skin protection.
Area of Science:
- Dermatology and Microbiology
- Immunology
Background:
- Probiotics and prebiotics are increasingly used in medicine due to their safety.
- These agents modulate the immune system and are explored for inflammatory skin conditions.
Purpose of the Study:
- To review the existing literature on the dermatological applications of probiotics and prebiotics.
- To assess their efficacy in various skin conditions, including atopic dermatitis, acne, wound healing, and photoprotection.
Main Methods:
- Systematic literature review of studies investigating probiotics and prebiotics in dermatology.
- Analysis of clinical trial data and observational studies.
Main Results:
- Probiotics and prebiotics may reduce the incidence of atopic dermatitis in infants.
- Their role in treating established atopic dermatitis is inconclusive.
- Emerging evidence suggests potential benefits for acne, wound healing, and photoprotection.
Conclusions:
- While promising for prevention and certain conditions, definitive recommendations for probiotic and prebiotic use in dermatology require larger, high-quality clinical trials.
- The safety profile supports continued investigation.
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