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[Lymphocytic meningitis. Virologic study. Analysis of the study carried out from 1984 to 1986 (632 cases)]

A Téllez, A Bernal, F de Ory

    Enfermedades Infecciosas Y Microbiologia Clinica
    |February 1, 1989
    PubMed

    Insights

    The most common causes of viral lymphocytic meningitis are mumps virus in children and varicella-zoster virus in adults. A diagnostic protocol improves identification of these viral infections.

    Area of Science:

    • Virology
    • Infectious Diseases
    • Neuroscience

    Context:

    • Analysis of 632 cases of lymphocytic meningitis from 1984-1986.
    • Focus on virological diagnosis at the Centro Nacional de Microbiología.
    • Examines clinical and epidemiological features over a 3-year period.

    Purpose:

    • To identify the primary viral agents causing lymphocytic meningitis.
    • To evaluate diagnostic methods and clinical presentations.
    • To establish an effective diagnostic protocol for acute lymphocytic meningitis.

    Summary:

    • Mumps virus (46.9%) and non-polio enteroviruses (25.3%) were the most frequent causes overall.
    • Varicella-zoster virus was predominant in adults (33.3%).
    • Approximately 50% of herpesvirus infections lacked suggestive clinical signs.

    Impact:

    • Highlights the importance of specific IgM detection, viral isolation, and intrathecal antibody production.
    • Proposes a diagnostic protocol yielding a high diagnostic rate (44.1-54.9%).
    • Aids in optimizing the diagnosis and management of viral meningitis.

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