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Prospective Retinal and Optic Nerve Vitrectomy Evaluation (PROVE) study: twelve-month findings
Maziar Lalezary1, Rohan J Shah2, Rahul K Reddy3
1Department of Ophthalmology, Vanderbilt University School of Medicine, Nashville, Tennessee; Southern California Desert Retina Consultants, Palm Desert, California.
Ophthalmology
|June 8, 2014
Summary
Vitrectomy improved visual acuity and retinal thickness but not to fellow eye levels. Inferior peripapillary retinal nerve fiber layer thickness decreased, and intraocular pressure increased in pseudophakic eyes after 1 year.
Area of Science:
- Ophthalmology
- Retinal Surgery
Background:
- Pars plana vitrectomy is a common surgical procedure.
- Understanding its long-term effects on ocular structures is crucial.
Purpose of the Study:
- To evaluate 1-year outcomes of vitrectomy for epiretinal membrane, macular hole, or vitreous opacities.
- To assess changes in visual acuity, retinal thickness, and intraocular pressure.
Main Methods:
- Prospective, controlled, observational study of 40 participants (80 eyes).
- Evaluated surgical (study) and fellow (control) eyes.
- Included intraocular pressure, central corneal thickness, gonioscopy, fundus photography, OCT, and perimetry.
Main Results:
- Visual acuity improved in study eyes but remained worse than fellow eyes.
- Inferior peripapillary retinal nerve fiber layer thickness decreased in study eyes.
- Intraocular pressure increased in pseudophakic study eyes and was higher in macular hole eyes compared to fellow eyes.
Conclusions:
- Vitrectomy improves visual acuity and retinal thickness, but not to the level of fellow eyes.
- A decrease in inferior peripapillary retinal nerve fiber layer thickness was observed.
- Increased intraocular pressure was noted in pseudophakic eyes post-surgery.
