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Updated: Apr 28, 2026
Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
Published on: August 13, 2019
Clinical results of implant placement in resorbed ridges using simultaneous guided bone regeneration: a multicenter
Ioannis Konstantinidis1, Tarun Kumar, Udatta Kher
1Department of Prosthodontics, TU Dresden, Dresden, Germany, ioannis.konstantinidis@uniklinikum-dresden.de.
Objectives:
The purpose of this case series was to evaluate the new bone formation following guided bone regeneration (GBR) with a calcium phosphosilicate (CPS), alloplastic bone putty at peri-implant dehiscence defects and to assess survival rate of implants placed in the augmented sites after 12 months of function.
Materials And Methods:
Implants were placed in patients exhibiting Seibert class I ridge defects resulting in peri-implant dehiscence defects. The defects were treated following GBR principles with the use of a CPS alloplastic bone graft putty in combination either with a collagen membrane or a titanium mesh. The height of each bony dehiscence was clinically measured at the time of implant placement and again during second-stage surgery. The percentage of complete defect coverage, frequency of adverse events, and risk factors for residual defect were determined.
Results:
Thirty-six implants were placed in 26 patients. Twenty-seven of the 36 sites employed a collagen membrane in conjunction with the CPS while the remaining nine sites utilized a titanium membrane. Mean gain in bone height was 3.23 ± 2.04 mm, with 75 % of the peri-implant defects achieving complete regeneration. A negative correlation was identified between patient age and complete coverage of the peri-implant defect (p = 0.026). The implant survival rate at 12 months was 97.22 %.
Conclusion:
Use of CPS bone putty during delayed implant placement at peri-implant dehiscence sites either in combination with a collagen membrane or a titanium mesh results in predictable defect coverage.
Clinical Relevance:
The handling characteristics of CPS putty may simplify GBR protocol. Implants placed in conjunction with GBR have a very good survival rate after 1 year of follow-up.
