Related Experiment Video
Updated: Apr 28, 2026
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
[The analysis of morphological and functional macular changes after surgical treatment of idiopathic macular
Purpose:
to evaluate morphological and functional macular changes after surgical treatment of idiopathic macular hole.
Material And Methods:
a retrospective study included 25 patients (30 eyes) who underwent surgery for idiopathic macular hole. Male patients constituted 27% and female patients 73% of the study group. Mean age was 67 years. All patients underwent pars plana vitrectomy with internal limiting membrane peeling and gas tamponade (C3F8 or SF6). We evaluated age, sex, best corrected visual acuity as well a optical coherence tomography scans prior to surgery and postoperatively. The mean follow-up was 6 months.
Results:
the mean preoperative best corrected visual acuity was 0.15 in Snellen charts (≤ 0.1 - 13 eyes, > 0.1 - 17 eyes) and it increased to 0.5 postoperatively. Five eyes were preoperatively classified as stage 2 Gass scale, 13 eyes as stage 3 and 13 eyes as stage 4. Postoperatively, 25 eyes were assorted as "U" shaped and 5 as "V" shape closure.
Conclusions:
surgical treatment of macular hole with pars plana vitrectomy significantly improves macular function measured by the best corrected visual acuity. The "U" shaped closure of macular hole promotes better visual outcomes.
