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Endoscopic sclerotherapy in children.

J B Dilawari1, Y K Chawla, G N Ramesh

  • 1Department of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Journal of Gastroenterology and Hepatology
|March 1, 1989
PubMed
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Endoscopic sclerotherapy effectively treated esophageal varices in children with portal hypertension, significantly reducing rebleeding rates. While complications occurred, the procedure proved successful in achieving variceal obliteration.

Area of Science:

  • Pediatric Gastroenterology
  • Hepatology
  • Endoscopic Procedures

Background:

  • Portal hypertension in children often leads to variceal bleeding, a serious complication.
  • Extrahepatic portal venous obstruction is a common cause of portal hypertension in pediatric patients.
  • Endoscopic sclerotherapy is a potential treatment to manage variceal bleeding.

Purpose of the Study:

  • To evaluate the efficacy and safety of endoscopic sclerotherapy for treating esophageal varices in children.
  • To assess the rate of variceal obliteration and rebleeding after sclerotherapy.
  • To document major complications associated with the procedure.

Main Methods:

  • Thirty-eight children (aged 1-15 years) with portal hypertension and recent variceal bleeding underwent repeated endoscopic sclerotherapy.

Related Experiment Videos

  • Thirty-six patients had extrahepatic portal venous obstruction.
  • The study tracked variceal obliteration, rebleeding rates, and complications.

    • Main Results:

    • Variceal obliteration was achieved in 35 (92%) of the 38 patients.
    • An average of 5.3 sclerotherapy sessions were required per patient.
    • Major complications, including esophageal perforations and strictures, occurred in seven patients.
    • Sclerotherapy significantly reduced rebleeding rates, especially after variceal obliteration.

    Conclusions:

    • Repeated endoscopic sclerotherapy is an effective treatment for esophageal varices in children with portal hypertension.
    • The procedure achieves high rates of variceal obliteration and reduces rebleeding.
    • Careful monitoring for complications such as esophageal perforation and stricture is essential.