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Updated: Apr 28, 2026

Author Spotlight: Dermatopathology and the Treatment of Sexually Transmitted Diseases
Published on: November 8, 2024
Bowenoid papulosis successfully treated with imiquimod 5% cream
Akira Shimizu1, Madoka Kato, Osamu Ishikawa
1Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Japan.
Abstract:
A 24-year-old healthy Japanese female was diagnosed as having bowenoid papulosis in the genital area. The histopathological findings revealed acanthosis, papillomatosis, dyskeratotic cells and clumping cells with mild atypical nuclei. Human papillomavirus type 16 was detected in the lesion. The lesion was successfully treated with topical imiquimod 5% cream after 2 months. Imiquimod 5% cream is a potentially effective treatment modality for lesions that are difficult to treat with surgical excision.
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