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Vitamin D: present and future.

M Varsavsky1, G Alonso2, A García-Martín3

  • 1Unidad de Endocrinología, Hospital Sant Pau i Santa Tecla, Tarragona, España.

Revista Clinica Espanola
|June 10, 2014
PubMed
Summary
This summary is machine-generated.

Vitamin D is crucial for bone health and has other benefits. Supplementation with calcium and vitamin D may reduce fracture and fall risks in older adults, with recommended daily doses.

Keywords:
Deficiencia de vitamina DFracturas de estrésFracturas osteoporóticasFractures, StressOsteoporosisOsteoporotic FracturesVitamin DVitamin D DeficiencyVitamina D

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Area of Science:

  • Endocrinology
  • Nutritional Science
  • Geriatrics

Background:

  • Growing interest in vitamin D beyond bone health, focusing on extra-osseous effects.
  • Established sufficiency levels for 25-OH vitamin D (serum concentration >30 ng/mL) and deficiency (<20 ng/mL).

Purpose of the Study:

  • To review the role of vitamin D in bone metabolism and extra-osseous functions.
  • To evaluate the efficacy of calcium plus vitamin D supplementation in the elderly.
  • To discuss various treatment options for vitamin D deficiency.

Main Methods:

  • Literature review of studies on vitamin D, bone health, and elderly populations.
  • Analysis of research on the impact of calcium and vitamin D supplements on fracture and fall risks.
  • Examination of different therapeutic approaches for vitamin D deficit.

Main Results:

  • Calcium plus vitamin D supplementation shows a positive effect in reducing fracture and fall risks in the elderly.
  • Recommended daily intake for effective supplementation is 700-1,000 IU.
  • Various forms of vitamin D (D2, D3, calcidiol, calcitriol) and selective vitamin D receptor activators are available for treatment.

Conclusions:

  • Vitamin D plays a vital role in both bone mineral metabolism and has significant extra-osseous effects.
  • Supplementation with calcium and vitamin D is beneficial for fall and fracture prevention in the elderly.
  • Appropriate treatment strategies exist for vitamin D deficiency, including different vitamin D analogs.