Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[HIV infection and monocyte function].

J L Pérez Castrillón, J L Pérez Arellano, J M Olmos Martínez

    Anales De Medicina Interna (Madrid, Spain : 1984)
    |February 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Profile of patients who consult with internists for an osteoporosis assessment: The OSTEOMED registry.

    Revista clinica espanola·2021
    Same author

    [Repetition of microbiological tests in suspect of SARS-CoV-2 infection: utility of a score based on clinical probability].

    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2020
    Same author

    Profile of patients who visit medical internists for an osteoporosis assessment: The OSTEOMED registry.

    Revista clinica espanola·2020
    Same author

    Medicine·2020
    Same author

    Response of osteocalcin and insulin resistance after a hypocaloric diet in obese patients.

    European review for medical and pharmacological sciences·2015
    Same author

    Ankle-brachial index, risk of clinical fractures, mortality and low bone mass in nursing home residents.

    European review for medical and pharmacological sciences·2015

    Human immunodeficiency virus (HIV) does not alter monocyte function in intravenous drug users (IVDUs). Monocyte adherence and chemotaxis were similarly decreased in both HIV-positive and HIV-negative IVDUs compared to controls.

    Area of Science:

    • Immunology
    • Virology
    • Cell Biology

    Context:

    • Intravenous drug users (IVDUs) represent a population at high risk for Human immunodeficiency virus (HIV) infection.
    • Monocyte dysfunction is implicated in various disease pathologies.
    • Understanding monocyte function in IVDUs is crucial for assessing HIV's role in disease progression.

    Purpose:

    • To investigate the specific role of HIV in altering non-specific monocyte function among IVDUs.
    • To compare monocyte function (adherence and chemotaxis) between HIV-positive and HIV-negative IVDUs.
    • To determine if HIV infection exacerbates pre-existing monocyte alterations in this population.

    Summary:

    • A study was conducted on 14 intravenous drug users (IVDUs) to assess monocyte function, specifically adherence and chemotaxis.

    Related Experiment Videos

  • Participants were divided into two groups: HIV-infected and HIV-uninfected.
  • No significant differences in monocyte adherence or chemotaxis were found between the HIV-positive and HIV-negative IVDU groups, with both showing similar decreases compared to a control group.

    • Impact:

    • This study suggests that HIV infection does not uniquely impair monocyte function in IVDUs beyond the alterations already present.
    • The findings indicate that non-specific monocyte dysfunction in IVDUs may be primarily related to drug use rather than HIV status.
    • Further research is needed to elucidate the precise mechanisms underlying monocyte alterations in IVDUs and their clinical implications.