Spindle Cell Lipoma of the Conjunctiva

Area of Science:

• Ophthalmology
• Dermatopathology
• Surgical Pathology

Background:

• Spindle cell lipoma is a rare, benign mesenchymal tumor typically occurring in the neck or upper back.
• Ocular surface tumors, while uncommon, require accurate diagnosis for appropriate management.

Observation:

• A 67-year-old female presented with a progressively enlarging, long-standing mass on her ocular surface.
• The mass caused significant ocular surface irritation.

Findings:

• En bloc excision of the ocular mass was performed.
• Histopathological examination revealed a well-defined, encapsulated tumor.
• The tumor comprised wiry collagen, bland spindle cells positive for CD34, and scattered mature adipocytes.

Implications:

• This case highlights the importance of considering spindle cell lipoma in the differential diagnosis of ocular surface masses.
• Accurate histopathological diagnosis, including immunohistochemistry (CD34), is crucial for distinguishing benign from potentially malignant lesions.
• Surgical excision is an effective treatment for symptomatic ocular spindle cell lipoma.