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Systemic abnormalities in children with congenital optic disc excavations
1Department of Ophthalmology, Queen Fabiola Children's University Hospital, Université Libre de Bruxelles , Brussels , Belgium.
Current Eye Research
|June 10, 2014
Summary
Congenital optic disc excavations in children are frequently associated with other health issues. A systematic screening for extra-ocular abnormalities is recommended, especially in cases with vision problems or developmental delays.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Medical Genetics
Background:
- Congenital optic disc anomalies, including excavated optic discs, are common optic nerve head abnormalities.
- These conditions often occur alongside optic disc hypoplasia.
Purpose of the Study:
- To retrospectively analyze screening results for extraocular abnormalities in children with congenital optic disc excavations.
- To identify associated ocular and systemic conditions in affected individuals.
Main Methods:
- Retrospective review of medical records for 37 patients with non-glaucomatous optic disc excavation.
- Analysis of extraocular evaluations and associated ocular abnormalities.
Main Results:
- Ocular abnormalities were present in 31% of eyes with excavated optic discs.
- At least one extra-ocular disorder was identified in 48% of patients.
- Optic disc excavation was considered syndromic in 30% of cases.
- Extraocular malformations were more prevalent in infants with ocular malformations or abnormal vision/development.
Conclusions:
- A systematic search for systemic abnormalities is advisable for patients with congenital excavated optic discs.
- This approach is particularly important for patients with abnormal vision, ocular defects, or developmental issues.
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