[Effects of Anhidrin on dog's dental pulp in vivo]

The purpose of the article was to investigate in vivo effects of Anhidrin, a cavity cleansing agent, on dog's dental pulp. Following class V cavity preparation, with a depth referred to caries media, dentine walls were cleaned with Anhidrin. Cavity floor was lined with denatured dentine powder and permanently filled with silver amalgam. Animals were sacrificed after experimental period of 14, 45 and 90 days, respectively. Decalcified tooth sections were prepared by standard histologic technique stained with HE. The results achieved using light microscopy showed the most intensive changes in pulp tissue beneath cavity preparations treated with Anhidrin 14 days postoperatively, characterized with hyperaemia and bleeding in odontoblast and subodontoblast layer, reduction in odontoblast number and disturbed cell arrangement. In the second experimental period after 45 days, the changes were less expressed. Ninety days after the operation pulp tissue appeared in normal histologic structure of sound dental pulp, with significant layers of tertiary dentine beneath the area of cavity preparation and application of Anhidrin.