Related Experiment Video
Updated: Apr 28, 2026
03:47
Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
Published on: November 1, 2024
471
Relationship between oral problems and Helicobacter pylori infection
YanSong Zheng1, MinYan Liu2, Hua Shu2
1The Chinese People's Liberation Army General Hospital Health Management Institute, FuXing Road 28, Beijing 100853, China.
Archives of Oral Biology
|June 10, 2014
Summary
Helicobacter pylori (Hp) infection is linked to poor oral hygiene, specifically dental calculus and loose teeth. Improving oral health may help prevent or eradicate Hp infection.
Area of Science:
- Oral health and infectious diseases
- Microbiology and public health
Background:
- Helicobacter pylori (Hp) infection is a significant global health concern.
- Understanding the relationship between oral health and Hp infection is crucial for public health strategies.
Purpose of the Study:
- To investigate the association between various oral problems and Hp infection.
- To identify specific oral issues significantly correlated with Hp infection.
Main Methods:
- A cross-sectional study involving 54,036 participants undergoing medical examinations.
- Assessment of 12 oral problems and confirmation of Hp infection using the (13)C-urea breath test.
- Collection of demographic and lifestyle data, including age, gender, BMI, smoking, and drinking habits.
Main Results:
- The prevalence of Hp infection was 46.97%, associated with age, gender, BMI, smoking, and regular drinking.
- After adjusting for confounding factors, dental calculus (OR=1.05) and loose tooth (OR=1.22) were significantly related to Hp infection.
- These findings suggest a potential role of dental plaque in Hp transmission or persistence.
Conclusions:
- Oral hygiene and the presence of dental calculus and loose teeth are associated with Hp infection.
- Focusing on oral health interventions, particularly addressing dental calculus and loose teeth, may be beneficial for Hp infection prevention and eradication.
- The study highlights the importance of integrating oral health into broader public health initiatives for infectious diseases.
More Related Videos
05:23Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance
Published on: March 7, 2025
889
03:33Rapid Detection of Fecal Antigen of Helicobacter pylori Infection Based on Double Antibody Sandwich Detection Technology
Published on: May 23, 2025
1.2K
Related Concept Videos
01:27Peptic Ulcer
46
Peptic ulcers are erosive lesions of the gastric or duodenal lining, most commonly caused by Helicobacter pylori infection. This Gram-negative, helical bacterium has adapted to survive the stomach’s acidic environment by producing urease, which converts urea into ammonia and carbon dioxide. The ammonia neutralizes gastric acid in the bacterium’s immediate environment, allowing colonization of the gastric mucosa. H. pylori attaches to mucus-secreting epithelial cells, penetrates the...
46
01:26Gastritis II: Pathophysiology
43
The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...
43
01:16Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy
2.5K
Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
2.5K
01:30Peptic Ulcer Disease I: Introduction
1.2K
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
1.2K
01:25Peptic Ulcer Disease I: Introduction
25
Peptic ulcer disease (PUD) involves breaks in the gastrointestinal tract's mucosal lining, primarily in the stomach and duodenum, with less frequent occurrences in the lower esophagus or near the pylorus.Ulcers can be acute or chronic. Acute ulcers are short-lived with minimal inflammation and heal quickly after the irritant is removed. Chronic ulcers persist, may recur, and often cause scarring due to ongoing tissue damage. Superficial erosions affect only the mucosal layer and are called...
25
01:24Peptic Ulcer Disease II: Pathophysiology
41
Peptic ulcer disease develops when protective mechanisms of the gastrointestinal mucosa are overwhelmed by harmful factors, leading to localized erosions in the stomach or proximal duodenum. The main causes are Helicobacter pylori infection and chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs).Helicobacter pylori–Induced InjuryBacterial Adaptation and Colonization:H. pylori is a spiral, Gram-negative bacterium adapted to the acidic stomach. and transmitted through oral-oral or...
41