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Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
Organic azides: "energetic reagents" for the intermolecular amination of C-H bonds
Daniela Intrieri1, Paolo Zardi, Alessandro Caselli
1Università degli Studi di Milano - Chemistry Department, Via Golgi 19, 20136 Milano, Italy. emma.gallo@unimi.it.
Abstract:
This feature article provides an overview of the application of organic azides for the intermolecular amination of sp(3) and sp(2) C-H bonds. The catalytic activity of several metal complexes was reviewed underlining both synthetic and mechanistic aspects of the C-H amination. The majority of the aminated compounds reported in literature have been collected in this paper to provide a compendium of published procedures. In addition, the discussion of involved mechanisms has been included to assist the reader to envisage the future potential of organic azides in the synthesis of aza-derivatives.
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