Behavioral health mediators of the link between posttraumatic stress disorder and dyslipidemia
Paul A Dennis1, Christi S Ulmer2, Patrick S Calhoun3
1Durham Veterans Affairs Medical Center, Durham, NC, 27705, USA.
Objectives:
Posttraumatic stress disorder (PTSD) has been linked to dyslipidemia, which is a major risk factor for coronary artery disease. Although this link is thought to reflect response to heightened stress, behavioral health risks, including smoking, alcohol dependence, and poor sleep quality, may mediate the relationship between PTSD and dyslipidemia.
Methods:
To test this hypothesis, serum lipid levels were collected from 220 young adults (18-39 years old), 103 of whom were diagnosed with PTSD.
Results:
PTSD and associated depressive symptoms were negatively related to high-density lipoprotein cholesterol (HDL-C), p=.04, and positively related to triglyceride (TG) levels, p=.04. Both associations were mediated by cigarette consumption and poor sleep quality, the latter of which accounted for 83% and 93% of the effect of PTSD and depression on HDL-C and TG, respectively.
Conclusions:
These results complement recent findings highlighting the prominence of health behaviors in linking PTSD with cardiovascular risk.
More Related Videos
Related Concept Videos
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Post-traumatic Stress Disorder
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
Introduction to Stress and Lifestyle
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Atherosclerosis III: Management
Coronary Artery Disease I: Introduction


