Related Experiment Video
Updated: Apr 28, 2026

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation
Published on: June 17, 2015
[Toxicological evaluation in the childhood]
Amparo Arroyo1, Carlos Rodrigo2, M Teresa Marrón1
1Instituto de Medicina Legal de Cataluña. Departamento de Justicia. Barcelona. España.
Insights
Infant intoxications necessitate prompt medical care and have legal implications. This study evaluates clinical management and medical-legal aspects, emphasizing public health surveillance for child protection.
Area of Science:
- Pediatrics
- Toxicology
- Forensic Medicine
Context:
- Infant intoxications constitute 0.3% of pediatric emergencies, often accidental but sometimes linked to abuse or adolescent suicide attempts.
- Effective medical care involves clinical diagnosis, identification of common toxicants, and appropriate referrals to social services and legal authorities.
- Accurate interpretation of toxicological findings is crucial for medical and legal assessments.
Purpose:
- To evaluate clinical healthcare and medical-legal aspects of infant intoxications.
- To analyze the medical assistance provided, including diagnosis, common toxicants, and referral pathways.
- To assess the forensic medical opinion and its role in judicial proceedings for child protection.
Summary:
- The study examines clinical and medical-legal facets of infant intoxications, detailing medical assistance, common toxic substances, and referral processes.
- It highlights the importance of interpreting toxicological results accurately and discusses legal implications, including forensic medical opinions.
- Findings underscore the need for judicial intervention in intoxication cases to protect infants and inform public health surveillance.
Impact:
- Provides a framework for managing infant intoxications, integrating clinical care with legal requirements.
- Enhances understanding of the medical-legal interface in pediatric toxicology, aiding judicial decision-making.
- Contributes to strengthening public health surveillance systems for early detection and prevention of infant intoxications.
Abstract:
Intoxications in infancy require urgent medical treatment within national health systems. In our country they represent 0.3% of paediatric urgencies. Most of them are accidental intoxications but is not infrequent to find some related to child abuse or to suicidal intentions, especially in adolescence. The objectives of the study are to evaluate both clinical health care and medical legal aspects in intoxications in infancy. Medical assistance is described and it includes clinical diagnosis, typology of the more common toxics, percentages and referral to social work and emergency care equipment units of the Ministry of Social Welfare and the Department of Health or, where appropriate, directly to prosecutors and courts for their intervention. In cases of detection of alcohol, drugs or medication in infants, the importance of the correct interpretation of the results of toxicological findings is discussed. Several studies for the interpretation of results concerning the detection of these toxics are reported. Both legal aspects and the forensic medical opinion are assessed. The findings will be analysed by the judicial authority in order to circumscribe responsibilities or to take appropriate decisions concerning the protection of infants' interests. In conclusion intoxication in infancy can lead to legal proceedings requiring specific actions for their protection. Both physicians and hospitals must comply with the legal requirement of the submission to the court of judicial parties. On the other hand, this information is an interesting step toward reinforcing public health surveillance.
Related Concept Videos
Toxicity Testing in Animals
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Toxicokinetics: Overview
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Drug Toxicity: Dose-Dependent Reactions
Drug Toxicity: Risk factors

