Related Experiment Video
Updated: Apr 28, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
A rare solitary neurofibroma of the frontal sinus
Hongxing Li1, Xiaoxiao Peng, Junqing Li
1From the *Department of Neurosurgery, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang; †Department of Neurosurgery, Shengli Oilfield Central Hospital affiliated to Binzhou Medical University; and ‡Department of Intensive Care Unit, Dongying People's Hospital, Dongying, Shandong, the People's Republic of China.
Abstract:
Neurofibromas are common peripheral nerve sheath tumors related to Schwann cell's proliferation and are usually associated with neurofibromatosis type 1. Although solitary neurofibroma that occurs in the paranasal sinus is reported occasionally, neurofibroma located in the frontal sinus is extremely rare. Here, we report a case of a young woman who had a heterogeneous lesion in the left frontal sinus, eroding its anterior and posterior wall with signs of intracranial invasion. Postoperatively, results of the histologic examination confirmed the diagnosis of solitary neurofibroma. In conclusion, solitary neurofibroma should be considered in the differential diagnosis of frontal sinus masses.

