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Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
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Prostate cancer epidemiology.

Ana Plata Bello1, Tomas Concepcion Masip

  • 1Servicio de Urología. Hospital Universitario de Canarias. Santa Cruz de Tenerife. España.

Archivos Espanoles De Urologia
|June 11, 2014
PubMed
Summary

Prostate cancer incidence is rising globally due to aging populations and improved diagnostics. While mortality decreases, it remains a significant health concern, influenced by genetic and environmental factors.

Area of Science:

  • Oncology
  • Epidemiology
  • Public Health

Background:

  • Prostate cancer is the second most common cancer in men globally.
  • Rising incidence and high prevalence present a significant public health challenge.
  • Geographic and ethnic variations in incidence and mortality are notable.

Purpose of the Study:

  • To analyze the current epidemiological landscape of prostate cancer.
  • To explore future perspectives and trends in prostate cancer.
  • To provide an evidence-based overview of prostate cancer epidemiology.

Main Methods:

  • Conducted a literature review on Medline.
  • Focused on highly relevant papers concerning prostate cancer epidemiology and etiological factors.
  • Selected manuscripts with the highest level of evidence for review.

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Main Results:

  • Global prostate cancer incidence shows an increasing trend.
  • Mortality rates have decreased, but prevalence remains high.
  • Demonstrated risk factors include age, ethnicity, and family history; environmental factors also play a crucial role.

Conclusions:

  • Increased incidence over 20 years is linked to aging populations, better diagnostics, and screening.
  • Prostate cancer is the sixth leading cause of cancer death worldwide.
  • Genetic and environmental factors likely explain ethnic and geographic disparities in prostate cancer.