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Green tea and anticancer perspectives: updates from last decade.

Masood Sadiq Butt1, Rabia Shabir Ahmad, M Tauseef Sultan

  • 1a National Institute of Food Science and Technology , University of Agriculture , Faisalabad , Pakistan.

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Green tea consumption shows potential anticancer benefits, particularly against various cancers. This review clarifies ambiguities and explores mechanisms, offering new research avenues for green tea

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Area of Science:

  • Nutritional Biochemistry
  • Oncology
  • Molecular Biology

Background:

  • Green tea is a widely consumed beverage with recognized health benefits.
  • Its bioactive compounds, such as epigallocatechin-3-gallate, are linked to potential health advantages.
  • Previous research suggests an association between green tea consumption and reduced cancer prevalence.

Purpose of the Study:

  • To review and clarify the anticancer perspectives of green tea and its components.
  • To address conflicting findings regarding green tea's role in cancer prevention.
  • To explore mechanisms and future research directions in green tea's chemopreventive potential.

Main Methods:

  • Literature review of cohort studies, randomized controlled trials, cell culture, and animal studies.
  • Analysis of molecular mechanisms, including apoptosis induction and cell cycle regulation.
  • Compilation of recent findings to resolve ambiguities in existing research.

Main Results:

  • Green tea exhibits anticarcinogenic and antimutagenic activities through various molecular pathways.
  • Studies indicate potential inverse associations between green tea intake and cancer risk.
  • Conflicting results exist, particularly in specific populations like smokers.

Conclusions:

  • Green tea and its bioactive components show promise as anticancer agents.
  • Further research is needed to clarify ambiguities and optimize therapeutic strategies.
  • This review provides a foundation for future investigations into green tea's role in cancer prevention and treatment.