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Updated: Apr 28, 2026

Prevention of Heat Stress Adverse Effects in Rats by Bacillus subtilis Strain

Prevention of Heat Stress Adverse Effects in Rats by Bacillus subtilis Strain

Published on: July 11, 2016

Stress responses in probiotic Lactobacillus casei.

Marzieh Hosseini Nezhad¹, Malik Altaf Hussain, Margaret Lorraine Britz

¹a Research Institute of Food Science and Technology , Mashhad , Iran.

Critical Reviews in Food Science and Nutrition

|June 11, 2014

Summary

Survival in harsh environments is critical for lactic acid bacteria (LAB). Understanding stress responses in Lactobacillus casei improves their use as starter cultures and probiotics.

Keywords:

Lactobacillus casei probiotics stress survival

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Area of Science:

Microbiology
Biotechnology

Background:

Lactic acid bacteria (LAB) are vital for industrial applications like milk fermentation and cheese ripening.
Lactobacillus casei group members are common in the gastrointestinal tract and have probiotic potential.
Environmental stresses impact LAB functionality, making stress response mechanisms crucial.

Purpose of the Study:

To provide an overview of stress response features in Lactobacillus casei.
To explore proteomic and gene expression patterns related to stress tolerance.
To enhance the application of Lb. casei as starter cultures and probiotics.

Main Methods:

Literature review on stress responses in Lb. casei.
Analysis of proteomic and gene expression data related to environmental stresses.
Synthesis of findings on survival mechanisms in harsh conditions.

Main Results:

Identification of key stress response mechanisms in Lb. casei.
Correlation of specific gene expression and proteomic patterns with environmental adaptation.
Demonstration of the biotechnological importance of understanding LAB stress responses.

Conclusions:

Understanding Lb. casei stress responses is essential for optimizing their industrial and probiotic applications.
Proteomic and gene expression insights can guide strain improvement for enhanced resilience.
Further research into LAB-environment interactions holds significant biotechnological promise.