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[Frequency of sensitization to mites, cockroach and shrimp in adults with respiratory allergy]
Eunice López-Rocha1, Karen Rodríguez-Mireles, Arturo Gaspar-López
1Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Av. Cuauhtémoc 330 06720 México, DF. aeri_05@hotmail.com.
Background:
Sensitization to mites and cockroach are a common cause of respiratory allergy, especially in children. There is little information about its cross-reactivity with shrimp, which is common in adult patients.
Objectives:
To determine the frequency of sensitization to house dust mites (Dermatophagoides pteronyssinus, Dermatophagoides farinae) and cockroach species Periplaneta americana, in adult patients attending to a third level hospital and to determine the frequency of sensitization to shrimp in patients with positive skin test to house dust mite and/or cockroach, in patients with clinical manifestations suggestive of allergy to shrimp.
Material And Method:
A retrospective study was done in which results were reviewed of 672 patients clinical records, attending to the Allergy and Clinical Immunology department in a third level hospital, those patients with positive skin test results to Dermatophagoides and/or Periplaneta americana were investigated for sensitization to shrimp through Prick-to-Prick test.
Results:
Data from 672 patients were obtained, 69.8% (469) males, with a mean age of 33.5 years. Dermatophagoides positivity was 72.2% (486/672), and its relationship with other invertebrates that also have tropomyosin was 5.6% (4.9% with cockroach and 0.74% with shrimp).
Conclusions:
In our population, house dust mite sensitization was similar to that reported in the international literature. There was low positivity to cockroach, probably due to geographical conditions. There is very little information about shrimp's cross-reactivity with Dermatophagoides, despite its clinical significance, which requires more specific studies such as measurement of specific IgE to tropomyosin.
Insights
Respiratory allergies to house dust mites and cockroaches are common. This study found low cross-reactivity between these allergens and shrimp in adult patients, suggesting further research into tropomyosin-specific IgE is needed.
Area of Science:
- Allergy and Immunology
- Environmental Allergens
- Food Allergy
Background:
- Respiratory allergies to house dust mites (Dermatophagoides) and cockroaches are prevalent, particularly in children.
- Limited data exists on cross-reactivity between these common aeroallergens and shrimp allergy in adults.
- Shrimp allergy is a significant concern for adult patients with allergic conditions.
Purpose of the Study:
- To assess the prevalence of sensitization to house dust mites and cockroach in adult patients.
- To determine the frequency of shrimp sensitization in patients with positive skin tests to house dust mites and/or cockroaches.
- To investigate potential cross-reactivity between aeroallergens and shrimp allergy.
Main Methods:
- Retrospective review of 672 patient records from an Allergy and Clinical Immunology department.
- Skin prick testing (SPT) for Dermatophagoides mites and Periplaneta americana cockroach.
- Prick-to-Prick testing for shrimp sensitization in patients with positive aeroallergen SPTs.
Main Results:
- House dust mite sensitization was found in 72.2% of patients.
- Overall cross-reactivity with tropomyosin-containing invertebrates was 5.6%, including 4.9% with cockroach and 0.74% with shrimp.
- Low frequency of sensitization to shrimp was observed in this adult population.
Conclusions:
- House dust mite sensitization rates align with international findings.
- Low cockroach sensitization may be geographically influenced.
- Further studies, including specific IgE to tropomyosin, are needed to clarify shrimp cross-reactivity with Dermatophagoides due to its clinical importance.
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