The association between objectively measured sitting and standing with body composition: a pilot study using MRI
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Updated: Apr 28, 2026

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos
Published on: March 21, 2021
L Smith1, E L Thomas2, J D Bell2
1Department of Epidemiology and Public Health, University College London, London, UK.
Objective:
To investigate the association between objectively measured sitting and standing, using a postural allocation technique, with MRI-assessed body composition.
Design:
The present study was a cross-sectional pilot study.
Setting:
Participants were examined at one centre located in London, UK.
Participants:
Normal weight Caucasian women (30.9±6.1 years; body mass index (BMI), 22.9±3.4 kg/m(2)) with desk-bound occupations were recruited to minimise variability in body composition outcomes. A convenience sample of 12 women was recruited in January 2014 from University College London.
Outcome Measures:
For each participant a number of body composition variables were attained from a single whole-body MRI session. Main outcome variables included: total and liver adiposity, visceral/subcutaneous fat ratio and BMI. Main exposure variables included: average sitting time, standing:sitting ratio and step count. Pearson correlations were carried out to examine associations between different activity categories and body composition variables.
Results:
There were significant correlations between average daily sitting and liver adiposity and visceral/subcutaneous abdominal fat ratio (r=0.66 and 0.64, respectively); standing:sitting ratio was moderately correlated with liver adiposity and visceral/subcutaneous abdominal fat ratio (r=-0.53 and -0.45); average daily step count was moderately correlated with liver adiposity, total adiposity and visceral/subcutaneous abdominal fat ratio (r=-0.45, -0.46 and -0.51, respectively).
Conclusions:
This pilot study has provided preliminary evidence of relationships between objectively measured sitting and standing and precise measures of body composition.
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