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Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay
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Cdk5 phosphorylation of EFhd2 at S74 affects its calcium binding activity

Edwin Vázquez-Rosa1, Eva N Rodríguez-Cruz, Sybelle Serrano

  • 1Department of Chemistry, College of Natural Sciences, University of Puerto Rico-Río Piedras Campus, San Juan, Puerto Rico, 00931; Protein Mass Spectrometry Core Facility, College of Natural Sciences, University of Puerto Rico - Río Piedras Campus, San Juan, Puerto Rico, 00931.

Protein Science : a Publication of the Protein Society
|June 12, 2014
PubMed
Summary

Cyclin-dependent kinase 5 (Cdk5) phosphorylates the calcium-binding protein EFhd2 at S74, impacting its function. This phosphorylation occurs in Alzheimer

Keywords:
Cdk5EFhd2calcium bindingphosphorylationtautauopathy

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