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Updated: Apr 28, 2026

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells
Published on: May 5, 2023
Application of iPS cells in dental bioengineering and beyond
Pengfei Liu1, Yanmei Zhang, Shubin Chen
1CAS Key Laboratory of Regenerative Biology and Guangdong Provincial Key Laboratory of Stem Cell Biology and Regenerative Medicine, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 190 Kai Yuan Avenue, Science Park, Guangzhou, 510530, People's Republic of China.
Induced pluripotent stem cells (iPS cells) show promise for regenerative medicine and tooth regeneration. This review discusses iPS technology
Area of Science:
- Biomedical Engineering
- Regenerative Medicine
- Stem Cell Biology
Background:
- Stem-cell-based tissue engineering is crucial for creating functional organs and tissues.
- Induced pluripotent stem cells (iPS cells) offer significant potential for regenerative medicine advancements.
- Previous research highlighted iPS cells as a viable source for tooth regeneration.
Purpose of the Study:
- To review the application of iPS technology in dental bioengineering.
- To discuss the challenges associated with using iPS cells for complete tooth regeneration.
Main Methods:
- Literature review of iPS cell applications in dental bioengineering.
- Analysis of current challenges in whole tooth regeneration using iPS cells.
Main Results:
- iPS cell technology is a promising area within dental bioengineering.
- Significant challenges remain in achieving whole tooth regeneration with iPS cells.
Conclusions:
- iPS cells are a key focus in regenerative dentistry.
- Further research is needed to overcome obstacles for iPS cell-mediated tooth regeneration.
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