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Metastatic malignant melanoma to the bladder: a case series
Eric S Wisenbaugh1, Melissa L Stanton1, Gwen M Grimsby1
1Mayo Clinic Arizona, Phoenix, Ariz., USA.
Background:
Metastatic melanoma to the bladder is rarely reported, and the role of surgery is still largely unknown. We review 4 such cases and highlight their management and outcomes. We also review the relevant literature.
Methods:
The Mayo Clinic tumor database was searched and 4 such cases were found.
Results:
All 4 patients were treated locally with transurethral resection. The only patient who had a solitary metastasis did relatively well, having no evidence of disease 10 months after his presentation, while the other 3 died within 6 months. The literature highlights various approaches to management, but there is no definitive evidence that radical cystectomy offers any benefit over transurethral resection.
Conclusion:
Resection may improve survival in the setting of a solitary metastasis, but there is no evidence that radical cystectomy offers any benefit over local resection. With diffuse disease, however, resection is likely only beneficial for treatment of hematuria.
