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A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
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Variable correlation of grid coordinates to core location in template prostate biopsy
Christopher M Brede1, Nicholas J Douville2, Stephen Jones1
1Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Current Urology
|June 12, 2014
Summary
Transperineal template biopsy accuracy varies. Prostate cancer biopsy precision depends heavily on technique, not just the grid, due to potential needle placement errors.
Area of Science:
- Urology
- Oncology
- Medical Imaging
Background:
- Transperineal template prostate biopsy is suggested for repeat biopsies in high-risk cancer patients.
- It's believed to offer more reliable location mapping than transrectal ultrasound guided biopsy.
Purpose of the Study:
- To assess if transperineal template biopsy ensures reproducible needle placement accuracy.
- To investigate the reliability of the grid system in mapping prostate biopsy locations.
Main Methods:
- A standard 0.5 cm brachytherapy grid was used for transperineal biopsies.
- Biopsies were taken through a single grid hole, varying needle bevel and angle.
- The grid's ability to "map" the prostate was tested by altering needle parameters.
Main Results:
- Significant variation in needle placement was observed even with a single grid hole.
- At 5 cm depth, biopsy area was 2.47 mm², precision 22%; at 25 cm, area was 7.56 mm², precision 7%.
Conclusions:
- Transperineal template guided prostate biopsy has potential for technical and equipment errors.
- The biopsy grid alone does not guarantee accuracy; technique is crucial for reliable cancer detection and staging.
