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Association between oxidative stress and nutritional status in the elderly
Priscila Lucelia Moreira1, Paulo Jose Fortes Villas Boas2, Ana Lucia Anjos Ferreira3
1Master?s degree and Doctorate student, Department of Clinical Medicine, Botucatu School of Medicine, Universidade Estadual Paulista, Botucatu, SP, Brazil.
Revista Da Associacao Medica Brasileira (1992)
|June 12, 2014
Summary
Oxidative stress increases with aging and is linked to poor nutrition. While antioxidant supplements show no proven benefit for the elderly, a diet rich in antioxidant foods and maintaining a healthy weight are recommended.
Area of Science:
- Gerontology
- Biochemistry
- Nutrition Science
Background:
- Aging is a complex process involving morphological, biochemical, functional, and psychological changes.
- Oxidative stress is implicated in the aging process and age-related diseases like Parkinson's and Alzheimer's.
- Nutritional status appears inversely related to oxidative stress in the elderly.
Purpose of the Study:
- To review current concepts of oxidative stress in the geriatric population.
- To examine the relationship between aging, nutritional status, and antioxidant supplementation.
- To provide evidence-based recommendations for antioxidant intake in older adults.
Main Methods:
- Literature review of studies on oxidative stress, aging, nutrition, and antioxidants.
- Analysis of evidence regarding antioxidant supplementation efficacy in the elderly.
- Evaluation of dietary recommendations for antioxidant intake in geriatric populations.
Main Results:
- A significant inverse relationship exists between oxidative stress and nutritional status in elderly individuals.
- Increased oxidative stress is observed in chronic age-related diseases.
- No consistent clinical evidence supports the efficacy of antioxidant supplementation in mitigating oxidative stress in the elderly.
Conclusions:
- Antioxidant supplementation is not recommended for the geriatric population.
- Elderly individuals should be encouraged to consume antioxidant-rich foods like fruits and vegetables.
- Maintaining a healthy body mass index (23–28 Kg/m²) is advised for older adults.
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