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Updated: Apr 28, 2026

Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro
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[Intraocular osteosarcoma in a dog].

L Wiesner1, S Schröder, S Gralla

  • 1Luisa-Katharina Wiesner, Klinikum Veterinärmedizin, Klinik für Kleintiere, Chirurgie, der Justus-Liebig-Universität Gießen, Frankfurter Straße 108, 35392 Gießen,

Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
|June 13, 2014
PubMed
Summary
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This case study details a dog diagnosed with intraocular osteosarcoma, which later developed spinal tumors and a tonsil melanoma. The study highlights the diagnostic challenges and progression of extraskeletal osteosarcoma in dogs.

Area of Science:

  • Veterinary Medicine
  • Oncology
  • Ophthalmology

Background:

  • Intraocular osteosarcoma is a rare and aggressive bone cancer affecting the eye.
  • Early diagnosis and treatment are crucial for managing ocular neoplasms in animals.

Observation:

  • A dog presented with an intraocular neoplasm, diagnosed via imaging studies as potentially perforating the globe and invading the orbit.
  • An orbital exenteration was performed, with histopathology confirming intraocular, extraskeletal osteosarcoma.

Findings:

  • Post-surgery, the dog developed acute paraparesis, prompting further diagnostic evaluation with magnetic resonance imaging (MRI).
  • MRI and necropsy revealed an additional axial osteosarcoma on the 6th lumbar vertebra and a malignant melanoma of the right tonsil.
Keywords:
Dogaxialextraskeletaleyeosteosarcomaspine

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Implications:

  • This case underscores the aggressive nature and potential for metastasis of extraskeletal osteosarcoma in dogs.
  • It emphasizes the importance of comprehensive diagnostic workups, including advanced imaging like MRI, for suspected canine cancers.