Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

First Pass Effect01:12

First Pass Effect

10.5K
Presystemic elimination, or the first-pass effect, is the metabolism of drugs that reduces their effective concentration at the site of action. Apart from the first-pass effect, the systemic bioavailability of the drug is also reduced by other factors, including incomplete absorption or chemical degradation of drugs.
Depending on the route of administration, drugs can be metabolized in the liver, intestine, lungs, and vasculature. Orally administered drugs are first absorbed through the...
10.5K
Buffer Effectiveness02:19

Buffer Effectiveness

47.7K
Buffer solutions do not have an unlimited capacity to keep the pH relatively constant . Instead, the ability of a buffer solution to resist changes in pH relies on the presence of appreciable amounts of its conjugate weak acid-base pair. When enough strong acid or base is added to substantially lower the concentration of either member of the buffer pair, the buffering action within the solution is compromised.
The buffer capacity is the amount of acid or base that can be added to a given volume...
47.7K
Effects of feedback01:24

Effects of feedback

1.1K
Feedback in control systems plays a critical role in shaping various operational parameters, extending beyond simple error reduction to influence stability, bandwidth, gain, impedance, and sensitivity. Understanding these effects requires examining a basic feedback system characterized by defined input, output, error, and feedback signals.
Feedback significantly modifies the gain of a control system. The gain of a system without feedback is altered by a factor of one plus GH, where G represents...
1.1K
Effects of Creep01:25

Effects of Creep

634
Creep in concrete, the gradual deformation under prolonged stress, significantly impacts the integrity of structures. For reinforced concrete beams, it can be a vital design consideration, as it increases deflection, sometimes necessitating additional design measures. In columns, especially slender ones under eccentric loads, creep can cause buckling, compromising their stability. However, creep can be beneficial in indeterminate structures by mitigating stresses that arise from shrinkage,...
634

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A novel strategy of "Separation Surgery Combined with Vertebroplasty and Interstitial Implantation of <sup>125</sup>I Seeds (SSVPI)" in managing thoracic metastases from lung adenocarcinoma with spinal cord compression.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2026
Same author

A Diammonium-Based Non-Dion-Jacobson Phase 2D Perovskite With High Durability for Efficient and Stable 2D/3D Perovskite Solar Modules.

Angewandte Chemie (International ed. in English)·2026
Same author

Engineering Side-Chain Steric Effects to Build Selective COF Channels for Polysulfide Suppression in Li-S Batteries.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Cost-effectiveness-oriented management (CEOM) of cardiovascular risks at primary healthcare settings in Anhui, China: a protocol for a cluster randomised controlled trial.

BMJ open·2026
Same author

Co-activation and signal crosstalk between parthanatos and mitophagy in light-induced retinal injury.

Journal of photochemistry and photobiology. B, Biology·2026
Same author

Blockade of the CCL2-CCR2 axis attenuates fibrosis and parasite load in vesicular echinococcosis by inhibiting the PI3K-AKT pathway that regulates angiogenesis and hepatic stellate cell apoptosis.

Parasites & vectors·2026
Same journal

Denoising algorithm of Φ-OTDR systems based on adaptive fractional wavelet transform denoising.

Optics express·2026
Same journal

Millisecond photon-to-photon latency and high-speed volumetric projection system for optogenetics.

Optics express·2026
Same journal

Polarization-encoded coaxial structured light for high-precision 3D surface profilometry.

Optics express·2026
Same journal

Discrete freeform optical design based on collaborative optimization of point cloud and local normals.

Optics express·2026
Same journal

Ultrafast ghost imaging with 25 GHz speckle switching and wavelength-division multiplexing.

Optics express·2026
Same journal

Atomic vapor cells fabricated by femtosecond laser welding of standard-optical-quality glass.

Optics express·2026
See all related articles

Related Experiment Video

Updated: Apr 28, 2026

Measuring Attention and Visual Processing Speed by Model-based Analysis of Temporal-order Judgments
13:00

Measuring Attention and Visual Processing Speed by Model-based Analysis of Temporal-order Judgments

Published on: January 23, 2017

9.2K

Edge effect modeling and experiments on active lap processing.

Haitao Liu, Fan Wu, Zhige Zeng

    Optics Express
    |June 13, 2014
    PubMed
    Summary
    This summary is machine-generated.

    Edge effects in large mirror fabrication are challenging. This study models edge tool influence functions (TIFs) for Computer Controlled Active Laps (CCAL) using experimental data and two distinct modeling approaches.

    More Related Videos

    Eye Tracking During A Complex Aviation Task For Insights Into Information Processing
    07:48

    Eye Tracking During A Complex Aviation Task For Insights Into Information Processing

    Published on: April 4, 2025

    1.5K
    Using Eye Movements Recorded in the Visual World Paradigm to Explore the Online Processing of Spoken Language
    09:27

    Using Eye Movements Recorded in the Visual World Paradigm to Explore the Online Processing of Spoken Language

    Published on: October 13, 2018

    10.3K

    Related Experiment Videos

    Last Updated: Apr 28, 2026

    Measuring Attention and Visual Processing Speed by Model-based Analysis of Temporal-order Judgments
    13:00

    Measuring Attention and Visual Processing Speed by Model-based Analysis of Temporal-order Judgments

    Published on: January 23, 2017

    9.2K
    Eye Tracking During A Complex Aviation Task For Insights Into Information Processing
    07:48

    Eye Tracking During A Complex Aviation Task For Insights Into Information Processing

    Published on: April 4, 2025

    1.5K
    Using Eye Movements Recorded in the Visual World Paradigm to Explore the Online Processing of Spoken Language
    09:27

    Using Eye Movements Recorded in the Visual World Paradigm to Explore the Online Processing of Spoken Language

    Published on: October 13, 2018

    10.3K

    Area of Science:

    • Optics and Photonics
    • Materials Science
    • Manufacturing Engineering

    Background:

    • Fabricating large primary mirrors presents significant challenges, particularly concerning edge effects with large polishing tools.
    • Computer Controlled Active Lap (CCAL) technology, utilizing large pads, also encounters edge effect issues during mirror grinding and polishing.

    Purpose of the Study:

    • To investigate and model the material removal rules associated with edge effects in the CCAL process.
    • To develop effective methods for characterizing edge tool influence functions (TIFs) in large-scale mirror fabrication.

    Main Methods:

    • Experimental determination of edge TIFs on a Φ1090-mm circular flat mirror using a 375-mm-diameter lap.
    • Modeling edge TIFs using two approaches: finite element analysis (FEA) for pressure distribution and a parametric equivalent pressure model.

    Main Results:

    • Material removal rules for edge effects in CCAL were experimentally obtained.
    • Both FEA-based pressure distribution and the parametric equivalent pressure model demonstrated effectiveness in modeling edge TIFs.
    • The study successfully characterized edge TIFs for CCAL processes.

    Conclusions:

    • The developed methods provide accurate modeling of edge TIFs in CCAL, crucial for mitigating edge effects in large mirror fabrication.
    • Accurate modeling of edge TIFs is essential for improving the precision and efficiency of large primary mirror manufacturing using CCAL technology.