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Toll-like receptor polymorphisms are associated with increased neurosyphilis risk

Christina M Marra1, Sharon K Sahi, Lauren C Tantalo

  • 1From the *Departments of Neurology and †Medicine, University of Washington, Seattle, WA.

Sexually Transmitted Diseases
|June 13, 2014
PubMed
Summary

Common single-nucleotide polymorphisms (SNPs) in toll-like receptors (TLRs) 1, 2, and 6 are linked to neurosyphilis. Specific TLR1, TLR2, and TLR6 SNPs increase the risk for both laboratory- and clinically-defined neurosyphilis.

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