Related Experiment Video
Updated: Apr 28, 2026

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
Published on: April 23, 2019
Evolution and convergence of state laws governing controlled substance prescription monitoring programs, 1998-2011
Corey S Davis1, Matthew Pierce, Nabarun Dasgupta
1Corey S. Davis is with the Network for Public Health Law, Southeastern Region, Carrboro, North Carolina. Matthew Pierce is with the Health Law and Justice Program, American University Washington College of Law, Washington, DC. Nabarun Dasgupta is with the Injury Prevention Research Center, University of North Carolina at Chapel Hill.
Objectives:
We sought to collect and characterize all laws governing the operation of prescription monitoring programs (PMPs), state-level databases that collect patient-specific prescription information, which have been suggested as a tool for reducing prescription drug overdose fatalities.
Methods:
We utilized a structured legal research protocol to systematically identify, review, and code all PMP statutes and regulations effective from 1998 through 2011. These laws were then abstracted along eleven domains, including reporting provisions, data sharing, and data access.
Results:
PMP characteristics vary greatly among states and across time. We observed an increase in the types and frequency of data required to be reported, the types of individuals permitted to access PMP data, and the percentage of PMPs authorized to proactively identify outlier prescribers and patients. As of 2011, 10 states required PMPs to report suspicious activity to law enforcement, while only 3 required reporting to the patient's physician. None required linkage to drug treatment or required all prescribers to review PMP data before prescribing. Few explicitly address data retention.
Conclusions:
State PMP laws are heterogeneous and evolving. Future studies of PMP effectiveness should take these variations into account.
Related Concept Videos
Drug Control Governance: Regulatory Bodies and Their Impact
Drug Regulation
Prescription, Nonprescription and Orphan Drugs
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Drug Classes and Categories
Drug Abuse and Addiction: Pharmacological Phenomena
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...

