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Cloned Schistosoma mansoni proteinase (hemoglobinase) as a putative serodiagnostic reagent
C L Chappell1, J Hackel, A H Davis
1Verna and Marrs McLean Department of Biochemistry, Baylor College of Medicine, Houston, Texas 77030.
Journal of Clinical Microbiology
|January 1, 1989
Abstract:
Expressed cDNA encoding a proteolytic enzyme from Schistosoma mansoni has been cloned recently. Circulating antibodies reacting with the recombinant protein have been detected in the blood of mice and humans infected with S. mansoni, S. japonicum, or S. haematobium. S. mansoni and S. haematobium infection can be distinguished by antibody titer.