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Related Experiment Video

Updated: Apr 28, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
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[Maculopathy and dengue fever].

B Jellab, C Fardeau, P Lehoang

    Bulletin De La Societe Belge D'Ophtalmologie
    |June 14, 2014
    PubMed
    Summary
    This summary is machine-generated.

    Dengue fever can cause vision loss due to macular edema. Interferon alfa-2b therapy effectively treated this complication, leading to vision improvement.

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    Area of Science:

    • Ophthalmology
    • Infectious Diseases
    • Virology

    Background:

    • Dengue fever is a mosquito-borne viral illness prevalent in tropical regions.
    • Ocular complications of dengue, though rare, can significantly impact vision.
    • Bilateral decreased vision is a concerning symptom requiring thorough investigation.

    Observation:

    • A 20-year-old female presented with bilateral vision decrease following dengue fever.
    • Fundus examination showed bilateral loss of foveal reflection.
    • Optical coherence tomography confirmed macular edema.
    • Positive dengue serology indicated a recent infection.

    Findings:

    • Interferon alfa-2b therapy was initiated for the dengue-related macular edema.
    • Macular edema resolved following treatment.
    • Significant visual acuity improvement was observed within 12 days.

    Implications:

    • This case highlights a potential ocular manifestation of dengue fever.
    • Interferon alfa-2b shows promise as a treatment for dengue-associated maculopathy.
    • Early diagnosis and intervention are crucial for visual recovery in dengue patients.