[Ocular manifestations of children living with HIV/AIDS in Kinshasa]

Insights

Ocular manifestations affect 36% of Congolese children with HIV/AIDS, with adnexal issues being most common. Severe immune deficiency increases the risk of vision loss, including blindness.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Pediatrics

Background:

  • Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) can cause various health complications in children.
  • Ocular manifestations are a significant concern in pediatric HIV/AIDS patients, potentially impacting vision and quality of life.

Purpose of the Study:

  • To determine the frequency of ocular manifestations in Congolese children (0-15 years) with HIV/AIDS.
  • To identify clinical and biological predictors of these ocular conditions.

Main Methods:

  • A prospective, descriptive, cross-sectional study was conducted with 100 HIV/AIDS-infected children.
  • Ophthalmic examinations included visual acuity, adnexa/cornea inspection, slit-lamp, and dilated funduscopy.
  • CD4 lymphocyte counts were assessed in 88 children.

Main Results:

  • 36% of children presented with ocular manifestations, with adnexal issues (18%) being most frequent.
  • Children with severe immune deficiency (CD4 count <15%) were more prone to visual symptoms.
  • Four children (5.9%) had visual impairment or blindness, all with severe immune deficiency.

Conclusions:

  • The 36% frequency of ocular manifestations in Congolese children with HIV/AIDS is comparable to other African studies and higher than in other continents.
  • Adnexal manifestations are the most common ocular findings.
  • Severe immune deficiency is a critical risk factor for vision-threatening ocular complications in pediatric HIV/AIDS.
Abstract

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