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Updated: Apr 28, 2026

Author Spotlight: Investigating the Effects of Compounds on Intestinal Tissue Using 3D Human Cell Line Models
Published on: September 1, 2023
[A model of inflammatory process in the abdominal cavity in experiment]
Abstract:
The model of chronic inflammatory process in abdominal cavity was elaborated in experiment on big laboratory animals. Intraoperatively in 12 laboratory pigs a chronic infiltrate was formatted between adducting and abducting intestinal loops with its mesenterium; in a region of gastroduodenal ligament and liver; between spleen and great omentum. Dynamics of the infiltrate formation was studied on the 60th, 90th, 120th and 180th day in accordance to data of bacteriological and histological investigations. Application of the method proposed permits to create chronic infiltrate with prognosticated course, to reduce the experiment duration and quantity of experimental animals used.
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