Related Experiment Video
Updated: Apr 28, 2026
Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes
Published on: March 22, 2022
Lack of harmonization of red blood cell distribution width (RDW). Evaluation of four hematological analyzers
Giuseppe Lippi1, Fernanda Pavesi1, Mirco Bardi1
1Laboratory of Clinical Chemistry and Hematology, Academic Hospital of Parma, Italy.
Objectives:
To assess analytical imprecision and comparability of red blood cell distribution width (RDW) on Abbott Sapphire, Mindray BC6800, Siemens Advia 2120 and Sysmex XE-5000.
Design And Methods:
Within-run imprecision was assessed on three pools and comparability using 132 inpatient samples.
Results:
The imprecision of RDW was comprised between 0.3 and 1.2%, but the values exhibited broad variation among different analyzers, with bias exceeding the desirable quality specifications.
Conclusions:
Harmonization of RDW is still an unmet need.
