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Systematic review and meta-analysis of behavioral interventions for fecal incontinence with constipation
Kurt A Freeman1, Andrew Riley2, Danny C Duke2
1Division of Psychology, Institute on Development & Disability, Oregon Health & Science University and Department of Public Health and Preventative Medicine, Oregon Health & Science University freemaku@ohsu.edu.
Insights
Behavioral interventions effectively treat fecal incontinence with constipation in children. However, more high-quality research is needed to clarify the best treatment strategies for pediatric fecal incontinence.
Area of Science:
- Pediatric gastroenterology
- Clinical trial analysis
- Evidence-based medicine
Background:
- Fecal incontinence management in children often involves behavioral approaches.
- The comparative effectiveness of these behavioral strategies is not well-established.
Purpose of the Study:
- To systematically review randomized controlled trials on behavioral treatments for fecal incontinence with constipation in children aged 4-18 years.
- To synthesize evidence using mixed treatment comparisons and random effects models.
Main Methods:
- Systematic review of randomized controlled trials.
- Mixed treatment comparisons (MTCs) and random effects models were employed.
- Risk of bias and quality of evidence were assessed.
Main Results:
- Behavioral interventions demonstrated greater effectiveness compared to control conditions for improving success rates and reducing soiling frequency.
- While 10 studies were considered for MTCs, reliable estimates were not obtained; four studies were used for pooled analysis.
Conclusions:
- Current evidence supports the use of behavioral treatments for pediatric fecal incontinence with constipation.
- Limited evidence necessitates further high-quality trials to elucidate the relative benefits of various behavioral strategies.
Background:
Multiple treatments exist for fecal incontinence. However, the relative and additive influence of commonly used behavioral approaches remains unclear.
Objective:
We conducted a systematic review of randomized controlled trials to synthesize the effects of behavioral treatment of fecal incontinence with constipation in children aged 4-18 years. Mixed treatment comparisons (MTCs) and random effects models were used to analyze outcomes. Risk of bias and quality of evidence were rated.
Results:
Although 10 studies were identified for MTCs, results did not yield reliable or valid estimates. Four studies were retained for random effects pooled outcome analysis. Results indicated that behavioral intervention was more effective than control conditions for author-defined success and soiling frequency.
Conclusion:
Although evidence supports behavioral treatments for fecal incontinence with constipation in children, available evidence is limited. More and higher-quality trials are needed to better understand the relative effects of different treatments, including behavioral strategies.
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