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Related Concept Videos

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Ascites

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DefinitionAscites is the buildup of fluid inside the peritoneal cavity. It occurs when fluid moves out of the vascular system faster than the peritoneal lymphatics can remove it. This fluid shift is most commonly seen in liver cirrhosis but can also appear in several other systemic disorders.EtiologyCirrhosis remains the leading cause of ascites. Other conditions that can contribute include:Heart failureConstrictive pericarditisAbdominal cancersNephrotic syndromeSevere protein–calorie...
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Diseases of the Liver and Gallbladder01:26

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Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
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Hepatic Drug Excretion: Enterohepatic Cycling01:17

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Enterohepatic cycling involves the active secretion of drugs and their metabolites into the bile via transporters in the canalicular membrane of hepatocytes. This secretion is an integral part of the digestive process, releasing these substances into the gastrointestinal (GI) tract.
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Hepatitis01:25

Hepatitis

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Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver.
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Hepatic Drug Excretion: Influencing Factors01:16

Hepatic Drug Excretion: Influencing Factors

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The biliary system of the liver, crucial for bile secretion and drug excretion, comprises intrahepatic bile ducts that merge to form the common hepatic duct. This duct, carrying hepatic bile, combines with the cystic duct, draining the gallbladder and forming the common bile duct, which empties into the duodenum. Bile, produced by hepatic cells lining the bile canaliculi, is composed primarily of water, bile salts, pigments, electrolytes, and lesser amounts of cholesterol and fatty acids. Bile...
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Hepatic Encephalopathy01:29

Hepatic Encephalopathy

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DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic...
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Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
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Hepatic and biliary ascariasis.

Anup K Das1

  • 1Department of Medicine and I/C Hepatology Clinic, Assam Medical College, Dibrugarh, Assam, India.

Journal of Global Infectious Diseases
|June 14, 2014
PubMed
Summary
This summary is machine-generated.

Hepato-biliary ascariasis (HBA), a common complication of ascariasis in tropical regions, often presents with acute abdomen and jaundice. While generally treatable with anthelminthics, further research is needed due to incomplete understanding of the infection.

Keywords:
Ascaris lumbricoidesBiliary ductal ascariasisClinical manifestationsComplications and principles of treatment Hepatobiliary ascariasisPathophysiologyRecurrent pyogenic cholangitisReview of pathogenesisRoundworm infestation

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Area of Science:

  • Medical Parasitology
  • Hepatology
  • Tropical Medicine

Background:

  • Ascariasis is a significant global helminthic burden, particularly affecting children in tropical areas.
  • Hepato-biliary ascariasis (HBA) is increasingly diagnosed due to advanced imaging and endoscopic techniques.
  • HBA can manifest in various ways, often leading to acute abdomen and jaundice.

Purpose of the Study:

  • To review the clinical manifestations, diagnosis, and management of Hepato-biliary ascariasis.
  • To highlight the association between HBA and Oriental or recurrent pyogenic cholangiopathy.
  • To emphasize the need for further research into the epidemiological and immunological aspects of Ascaris infection.

Main Methods:

  • Review of clinical presentations and diagnostic approaches for HBA.
  • Analysis of treatment modalities, including conservative and interventional therapies.
  • Discussion of the link between HBA and pyogenic cholangiopathy.

Main Results:

  • Diagnosis relies on high clinical suspicion in endemic areas, confirmed by imaging or endoscopy.
  • Most HBA cases are managed conservatively with anthelminthic agents.
  • Oriental or recurrent pyogenic cholangiopathy is a recognized complication in Southeast Asia.

Conclusions:

  • HBA requires a high index of suspicion for timely diagnosis and management.
  • While mortality is low, incomplete understanding necessitates further research for optimal treatment strategies.
  • Ascariasis poses a significant socioeconomic threat due to its widespread impact on public health.