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Bullous mastocytosis mimicking congenital epidermolysis bullosa

Julio Cesar Salas-Alanis1, Cesar Eduard Rosales-Mendoza2, Jorge Ocampo-Candiani3

  • 1Basic Science Department, School of Medicine, Universidad de Monterrey, Monterrey, Mexico ; Dystrophic Epidermolysis Bullous Research Association Mexico (DebRA Mexico A.C.), Monterrey, Mexico ; Department of Dermatology, University Hospital, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico.

Case Reports in Dermatology
|June 14, 2014
PubMed

A 2-month-old female infant was referred to DebRA Mexico from the Regional Children's Hospital because of a generalized dermatosis from birth characterized by multiple blisters and erosions on the trunk, face and limbs, associated with minor trauma. A skin biopsy showing subepidermal blisters associated with a dermal infiltrate of Giemsa-positive cells and CD117-positive antibody was consistent with the diagnosis of bullous mastocytosis. Treatment with oral antihistamines, topical steroids, and antibiotics was initiated, leading to a remission of the lesions.

Keywords:
Bullous epidermolysisBullous mastocytosisDarier's sign

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