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Priapism associated with risperidone treatment.

P Sirota1, I Bogdanov

  • 1Abarbanel Mental Health Center, Tel Aviv University, Israel.

International Journal of Psychiatry in Clinical Practice
|June 14, 2014
PubMed
Summary
This summary is machine-generated.

Priapism, a persistent erection, is a rare side effect of risperidone, a psychotropic medication. This case study highlights a 19-year-old patient experiencing this adverse event after short-term risperidone treatment.

Keywords:
Risperidone Alpha-1 Receptor 5ht 1c/1D Receptors Priapism Alpha-2 Receptor

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Area of Science:

  • Pharmacology
  • Urology
  • Psychiatry

Background:

  • Priapism is a prolonged, painful erection unrelated to sexual stimulation.
  • Common causes include idiopathic factors, substance abuse, and sickle-cell anemia.
  • It is an uncommon adverse effect of psychotropic drugs, linked to alpha-adrenergic blockade.

Purpose of the Study:

  • To report a case of priapism in a young patient treated with risperidone.
  • To highlight the potential risk of priapism with psychotropic medication use.

Main Methods:

  • Case report of a 19-year-old male patient.
  • Review of adverse effects associated with risperidone treatment.

Main Results:

  • The patient developed priapism after four days of risperidone 2 mg/day.
  • No other contributing factors were identified.

Conclusions:

  • Risperidone can be a potential cause of priapism, even at low doses.
  • Clinicians should be aware of this rare but serious adverse effect.